Australian company Cortical Labs has unveiled the CL1, the world’s first commercial biological computer powered by human brain cells. This innovative system, launched in Barcelona on March 2, 2025, represents a significant leap forward in computing technology, combining living neural networks with traditional silicon hardware.
The CL1 operates using lab-grown human neurons that form dynamic and adaptive neural networks. These networks exhibit learning capabilities far surpassing those of conventional silicon-based artificial intelligence systems. The integration of biological components allows the CL1 to process information in a manner akin to the human brain, offering enhanced efficiency and adaptability.
Unique architecture enable learn and adapt rapidly
Cortical Labs’ CEO, Hon Weng Chong, stated that the CL1’s unique architecture enables it to learn and adapt rapidly, making it a versatile tool for various applications, including medical research and artificial intelligence development. The system’s ability to form and reconfigure neural connections in real-time opens new avenues for machine learning and data processing.

This development is part of a broader movement toward integrating biological elements into computing systems. Researchers worldwide are exploring the potential of organoid intelligence, which utilizes lab-grown brain organoids for computational tasks. Such systems aim to harness the inherent efficiency and learning capabilities of biological neurons to create more powerful and energy-efficient computing platforms.
Merging living cells with electronic circuits
The CL1’s launch marks a pivotal moment in the evolution of computing, demonstrating the feasibility of merging living cells with electronic circuits to create hybrid systems. As this technology advances, it may lead to more sustainable and efficient alternatives to traditional computing architectures, potentially transforming industries ranging from healthcare to artificial intelligence.
However, the integration of human brain cells into computing devices raises ethical considerations. Questions about consciousness, data privacy, and the extent of human augmentation are becoming increasingly pertinent as technology continues to evolve. Researchers and ethicists are actively engaging in discussions to address these concerns, ensuring that the development of such technologies aligns with societal values and ethical standards.
As Cortical Labs’ CL1 enters the market, it sets the stage for a new era in computing, where the convergence of biology and technology offers unprecedented possibilities and challenges.